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Report by Dr Phillip M. Katelaris, Urological Surgeon, Sydney Adventist Hospital
The 2004 meeting of the American
Urological Association occurred in
San Francisco in May. This meeting
affirmed that prostate cancer mortality
in the western world has decreased by
a factor of 20-25% since the early
1990s. The paper of Holmberg was
much discussed. This publication was
the first randomized control study that
demonstrated a significant survival
advantage for men managed by radical
retropubic prostatectomy as opposed to
watchful waiting for early prostate
cancer. These were positive messages
for patients and surgeons alike. The
worldwide acceptance of radical
prostatectomy for localised prostate
cancer has occurred due to excellent
results as judged by cancer cure,
preservation of continence and
preservation of potency. In well trained
surgical hands, it is a low morbidity
procedure with a negligible mortality
rate.
In contemporary practice most men
undergoing radical retropubic
prostatectomy are discharged by day 4 or
day 5 post operatively. Significant
complications are rare and most men
have good urinary control by four weeks
post operatively. A significant number of
pre-operatively younger potent men have
return of sexual function over a period
ranging from 6-36 months. During this
time potency is aided by the use of
penile injection therapy and/or oral
agents. Excellent sexual rehabilitation by
the use of inflatable penile prosthetics
can be achieved by men who were preoperatively
impotent or who do not
regain potency post operatively.
Significant complications such as rectal
perforation, bladder neck stricture and
anastomotic leak are rare when radical
prostatectomy is performed by an
experienced surgeon.
Contemporary anatomical retropubic
prostatectomy, as popularised by
Professor Patrick Walsh, is the gold
standard treatment for the management
of localised prostate cancer against
which all other treatment methods must
be compared. It is an operation in which
excellent outcomes can be achieved for
patients with standard operating
equipment available at a district hospital
level. Quality outcomes are achieved not
by high technology, but rather by
excellent surgical training and attention
to detail. The AUA meeting in San
Francisco saw a very significant
commercial push for the introduction of
so called “robot assisted” laparoscopic
radical prostatectomy. This is a
technique developed and popularised by
two French urologists who perform the
procedure repetitively and on a daily
basis. These very experienced French
surgeons have achieved low morbidity,
quality outcomes with their robot
assisted technique.
However, their results are not better than
the open operation performed in the
standard fashion. There is no
improvement in continence, potency or
margin positivity.
At this stage it appears to me that robot
assisted laparoscopic radical
prostatectomy is an expensive high
technology means of achieving the same
outcome. What is the advantage? There
is no advantage with respect to the key
parameters of margin positivity,
continence and potency. Hospital stay
may be shortened by one or two days.
This is of dubious significance to the
individual patient when reviewed in the
context of the remaining 10-20 years of
his life.
The dark side of robot assisted
laparoscopic radical prostatectomy is
that it is a potentially lethal operation in
the hands of an inexperienced surgeon.
The excellent results reported by the
French school cannot be readily
translated to surgeons who are not
performing the robotic technique
continually and in large numbers. Major
and worrisome complications of robotic
assisted surgery were reported at the
conference including urinary peritonitis,
a complication not seen in the standard
open technique.
The question remains; is robot assisted
laparoscopic radical prostatectomy
merely a high tech expensive way of
achieving the same outcome or worse,
or is it truly a surgical advance? Until
this question is answered, the
introduction of this technology should
proceed with extreme caution. It is
well said that there is no such thing as
a brave surgeon. It is the patient that
takes the risk.
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